Endocrine Abstracts

Introduction: Cushing’s disease is diabetogenic due to the insulin resistance generated by the stimulating effect of glucocorticoids on neoglucogenesis and hepatic glycogenolysis.GoalAim of our work is to study the frequency and characteristics of diabetes mellitus during Cushing’s disease.Material and Methods: Retrospective study of a sample of 100 patients collected between (January 1983 –...

IntroductionType 2 diabetes mellitus chronic hyperglycemia resulting from a defect in the secretion of insulin or the action of insulin or from these two associated abnormalities.Aim of the studyTo try to establish an optimal threshold of HbA1C to predict diabetes mellitus on a sample of Algiers population not known to be diabetic but at high risk compared to the gold standard OGPO.Meth...

IntroductionWhen we talk about the prevalence of diabetes on a planetary scale, we can speak of a global epidemic or even a pandemic. Its prevalence continues to increase and the detection of individuals at risk of developing this disease remains a major concern.Aim of the studyTo attempt to establish standards for HbA1c by assessing the validity of this test in the diagnosis of pre-diabetic conditions and in...

IntroductionThe prevalence of diabetes and pre-diabetes is steadily increasing. It affects 3 new cases every 10 seconds and more than 6 million per year. Objective: to determine the risk factors associated with diabetes in an Algiers population not known to be diabetic but at high risk.Methods500 patients aged 40 and over consulting at the level of primary care structures, volunteers but at high risk of diabe...

Introduction3ßeta Hydroxysteroid Dehydrogenase (3ß HSD) deficiency is a very rare autosomal recessive disorder affecting the synthetic pathways of all active steroids in the adrenals and gonads.ObservationThe 4-year-old child M.A and his 8-year-old sister M.M, from a consanguineous marriage, with a family history of sexual ambiguity. The clinical examination found a sexual ambiguity in the boy: &#15...

IntroductionCushing’s disease described in 1973 by Harvey Cushing is the most frequent cause of endogenous hypercorticism in adults in 80-85% of cases of Cushing’s syndromes, it is secondary to a pituitary microadenoma most often, its treatment is first-line neurosurgical.Aim of the studyTo evaluate the results of the short and medium term therapeutic management of Cushing’s disease and to try ...

IntroductionNon-functional pituitary adenomas (AHNF) are large tumors expressed primarily by neuro-ophthalmological signs in the foreground and pose a problem of therapeutic management and prognosis.Materials and methodsWe report a retrospective study of 50 files of ’non-functional’ pituitary adenomas collected between 1993 – 2005 with the aim of evaluating the results of surgery and convention...

IntroductionGraves’ disease is an autoimmune thyroid disease manifested by hyperthyroidism, homogeneous goiter and sometimes ophthalmopathy. The frequency of the disease is less than 1% with a female predominance of 5–10/1 male. Its treatment is difficult because of the evolving vagaries of this disease. We report the results of surgery for Graves’ disease through a retrospective study.Material and methods<p clas...

Introduction: Type 2 diabetes is a painless and silent pathology, often overlooked, 30% to 50% underdiagnosed. Its prevalence is constantly increasing. It affects 3 new cases every 10 seconds and more than 6 million per year.Aim of the work: Compare the HbA1c test to the carbohydrate status established by the HGPO on a sample of an unknown Algerian population with diabetes but at high risk. And try to establish HbA1c thresholds by appreciating the validi...